Posted by Optivida Health on

Reduction in endocannabinoid signaling may be responsible for some of the uncomfortable symptoms associated with menopause such as hot flashes, night sweats, depression, anxiety, headaches and weight gain.

Estrogen levels are linked to endocannabinoid levels, and both peak during ovulation. This does not occur during perimenopause and menopause.

An enzyme that controls estrogen levels, called fatty acid amide hydrolase (FAAH), breaks down an endocannabinoid molecule that is regulated by estrogen. In fact, activation of estrogen receptors and cannabinoid receptors found on the same cells often synergize to produce greater effects.

All parts of the endocannabinoid system are present in the human ovary, including the endocannabinoid called anandamide and its receptors, CB1 and CB2. Anandamide has a role in egg maturity and release during the menstrual cycle.

Endocannabinoid deficiency, a state in which levels of anandamide are too low, may initiate early menopause. Interestingly, underweight women or women with anorexia, who enter menopause early, also have low endocannabinoid levels. Boosting endocannabinoid levels or stimulating cannabinoid receptors with Hemp Extract may help prevent early menopause.


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Anxiety and depression are often intensified during menopause. Estrogen recruits the ECS to regulate emotional response through its actions on the brain. Lowered levels of estrogen during and after menopause mean less activation of the ECS, and poor ability to respond to stress and elevate mood accordingly.

The ECS regulates the bone loss seen after menopause. Cannabinoid receptor type 2 (CB2) is found on bone cells, called osteoblasts. A common mutation in the gene that codes CB2 in humans, resulting in fewer CB2 receptors, is associated with osteoporosis after menopause. Supplementing with Hemp Extract helps to support healthy bone growth and repair.

Estrogen recruits the ECS to regulate emotional response and relieves anxiety and depression through its actions on the brain. The reduced estrogen levels during and after menopause cause decreased activation of the ECS, and a poor ability to respond to stress and elevate mood accordingly. Again, adding Hemp Extract as part of a daily program will assist in managing menopausal stress and moods.

Hemp Extract provides protection from breast cancer. It has been shown to kill breast cancer cells independent of its activity on cannabinoid receptors while being protective to breast cells.

It makes sense to include Hemp Extract in a program to help maintain and balance the hormonal system as well as overall hormonal health. It is also a great support to alleviate menopausal and postmenopausal symptoms.

It is well established that Hemp Extract assists with a gentle menopause experience by improving moods, reducing stress, building bones, balancing hormones, protecting brain cells, relieving headaches and migraines, and balancing the endocrine system.


Thank you for taking your time to become educated on the science and technologies behind the best health supplements.

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My best wishes for your best health.

Frank Davis,
Founder and CEO of Optivida Health

[For more science-based evidence for the use of hemp extract read "Hemp Health Revolution: The A to Z Health Benefits of Hemp Extract"]


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